Based on article 16d1, article 16f and article 16h of d irective 200183ec traditional use. Arctostaphylos uvaursi lady bird johnson wildflower center. Description of the herbal substances, herbal preparations or combinations thereof. It is a fruitbearing plant, and grows in cooler climates suitable for similar berries bears eat. Arctostaphylos uva ursi leaf extract is an extract of the leaves of the bearberry. The transmitter vector is mainly the mosquito aedes aegypti and albopictus. Arbutin has herbal origin and can be found in leaves of some plants such as arctostaphylos uva ursi 415%, vaccinium vitis 5.
Trichome variation and the ecology of arctostaphylos in michigan. The herbal medicine consisted of bearberry and dandelion root and leaf. Arbutin is metabolized to hydroquinone and hydroquinone derivatives that make it potentially useful for urinary conditions. Tyrosinase inhibitory effect of chinese tamarisk extract on melanogenesis of b16 melanoma.
Vancouver jade kinnikinnick conservation garden park. Sanguisorba officinalis root extract has fgf5 inhibitory. A crude ethanolic extract of bearberry leaves was dechlorophyllized using a silicic acid column, and then fractionated by sephadex lh20 column chromatography using ethanol 95%, vv and acetone 50%, vv as the mobile phases. Arctostaphylos uvaursi landscape plants oregon state. Pdf biological activity of leaf extract and phenol. The upright branches are generally up to about 6 or 8 inches tallreportedly to 12 inches in extreme cases. About arctostaphylos uvaursi bearberry leaf extract. The uva ursi leaves may be smoked to relieve a headache.
The medicinal portion of uva ursi is the dried leaves, which, in addition to providing arbutin, contain methylarbutin, flavonoids, allantoin, tannins, gallic. Uva ursi folium bearberry leaf has been traditionally used to treat symptoms of lower urinary tract infections. Uvaursi extract and ibuprofen as alternative treatments. Arctostaphylos uvaursi growing guide how to grow common. T easycloning vector system promega, madison, wisconsin, usa. Arctostaphylos uvaursi is a plant species of the genus arctostaphylos widely distributed across. Sprengel extract possesses marked antioxidant activity in model and meat systems. Field and garden studies of arctostaphylos uvaursi ericaceae in north america.
H koehler, j franz, g bioavailability of drug preparations containing a leaf extract of arctostaphylos uvaursi uvae. European union herbal monograph on arctostaphylos uvaursi. The leaves of this small shrub have been used as an herbal folk medicine for centuries as a mild diuretic and astringent, and in the treatment of urinary tract infections such as cystitis, urethritis and nephritis, pyelitis and in pyelonephritis. As for skincare bearberry is interesting because it contains the wellknown skin lightening agent arbutin. What are bearberries and why are they good for your skin. In vitro efficacy of extracts of arctostaphylos uvaursi l. Point reyes features good, deepgreen foliage color and leaves closelyspaced on the stems. Arctostaphylos uva ursi leaf extract is an extract of the leaves of the bearberry, arctostaphylos uva ursi functions. United states, ca, berkeley, regional parks botanic garden at tilden. Ethanol extract had the highest amount of the total phenolic content 300.
From 1820 to 1950, uva ursi leaf was listed on the us national formulary as a. Arctostaphylos uva ursi leaf extract is an extract of the leaves of the bearberry, arctostaphylos uva ursi l. Kinnikinnick first nations for smoking mixture is a common name in canada and the united states. European union herbal monograph on arctostaphylos uvaursi l.
Pretty clusters of lanternshaped, whitetopink flowers hang gracefully from the short red. Committee on herbal medicinal products hmpc assessment report on arctostaphylos uva ursi l. Phenolic compounds from five ericaceae species leaves. Arctostaphylos uva ursi also called arctostaphylos, bearberry. The dried leaves were smoked by a number of native american groups living along the pacific ocean over the past two centuries, but there is little evidence of these groups smoking it prior to their.
Seeds have impermeable seed coats and dormant embryos. Moreover, it is well known that arctostaphylos uva ursi extract has been used in traditional medicine to treat urinary tract infections schindler et al. The objective of the present study was to examine sehplc as a tool to separate and partially characterise myosintannins complexes. Native americans and early pioneers smoked the dried uvaursi leaves and bark alone. Arctostaphylos, one of the chaparral iconic shrub genera, provides an example of. Vectors include mosquitoes and a wide range of other bloodfeeding diptera, lice, fleas, mites, and ticks. Uvaursi maxv, provided by douglas laboratories, supplies 200 mg of standardized uva ursi and 100 mg of nonstandardized leaf in a vegetarian capsule. Native americans and early pioneers smoked the dried uva ursi leaves and bark alone. Uva ursi scientifically called arctostaphylos uva ursi is a small shrub with rooting uva ursi extract is pulled from the leaves of the plant, which have long been. Herbal substances bearberry leaf uvae ursi folium consists of whole or cut, dried leaf of arctostaphylos uva ursi l. It contains not less than 7% of anhydrous arbutin c 12 h 16 o 7.
Arctostaphylos uva ursi leaf extract arctostaphylos uva ursi leaf extract is classified as. In vitro efficacy of extracts of arctostaphylos uva ursi l. About arctostaphylos uva ursi bearberry leaf extract. Arctostaphylos uvaursi an overview sciencedirect topics. Arctostaphylos uva ursi leaf extractf fucus vesiculosus extracta hereinafter referred to as brown algae extract eriobotrya japonica leaf extract ja. The leaves of the bearberry arctostaphylos uva ursi l. Sehplc separation of myosin complex with tannins of. Marketed health products directorate, health canada. A methanolic extract of uva ursi enhanced the inhibitory effects of. Ar is the main constituent of bearberry leaves dry extract, which is. Chromatographic separation of tannin fractions from a bearberry leaf arctostaphylos uvaursi l. During that time, 18% of women in the placebo group 27 individuals and 0% in the treatment group 30 individuals developed a uti. Arctostaphylos uvaursi is a plant species of the genus arctostaphylos widely distributed across circumboreal regions of the subarctic northern hemisphere. Arctostaphylos uvaursi, also known as uva ursi or bears grape, is a plant found in north america and eurasia.
Arctostaphylos, one of the chaparral iconic shrub genera, provides an. The foliage turns red or purplish in winter before becoming green again in spring. To explore the characteristics, medicinal uses and prescribing considerations of this herb in more detail, check out the references indicated. According to wikipedia the uva ursi part means grape of the bear. The red bearberry arctostaphylos rubra, which produces red berries of the three species listed above, the common bearberry, or arctostaphylos uva ursi, is the species that has used as an ingredient in dietary supplements and skin care products. Risk assessment of free hydroquinone derived from arctostaphylos uvaursi folium. This form of use is illegal or carefully regulated in many regions, due to the narcotic effect of the plant.
Uva ursi arctostaphylos uva ursi, also known as bearberry, is a lowlying evergreen shrub found in canada, europe, and asia. Extremely winter hardy, arctostaphylos uvaursi bearberry is a slowgrowing, creeping, evergreen shrub with trailing red stems studded with small, leathery, shiny, obovate, dark green leaves, up to 1 in. In herbalism, leaf tea is used to treat urinary tract inflammation. Plants profile for arctostaphylos uvaursi kinnikinnick. Ericaceae leaves and preparations made from them are used in traditional and modern medicine for urinary tract infections saric, 1989. Red berries are eaten by birds but not recommended for human consumption. A preliminary trial reported the effectiveness of uva ursi in preventing recurrent uti when combined with dandelion root and leaf. The species name of uva ursi is apparently from the latin uva grape and ursus bear. An extract from the gum resin of a tree and also a source of indian frankincense, this plant extract has both positive and negative qualities for skin. Uva ursi arctostaphylos uva ursi is best known for its use in urinary conditions especially the treatment of urinary infections and an enlarged prostate. Ingredient dictionary cosmetic ingredient dictionary. It is a 100% natural ingredient obtained through a cold extractive process that is able to preserve its unaltered antioxidant and antityrosinase phytocomplex.
Uva ursi the leaves of uva ursi arctostaphylos uva ursi have been used for centuries in herbal medicine to support the health of the urinary tract. Pdf phenolic compounds from five ericaceae species leaves. The leaves of uva ursi are traditionally brewed into a tea and used to improve urinary health. Arctostaphylos uva ursi leaf extract is an extract of the leaves. Uva ursi arctostaphylos uva ursi kathi j kemper, md, mph. Arctostaphylos uvaursi is a low creeping shrub with widely spreading branches at the soil surface that often produces a matlike growth form. From 1820 to 1950, uva ursi leaf was listed on the us national formulary as a urinary antiseptic. Synthetic and fragrant plant extracts, plant extracts. Arctostaphylos uva ursi is a little plant with nice red berries that lives in the north and is also called bearberry or kinnikinnick.
Arctostaphylos uvaursi bearberry or umbabazane leaf extracts contain arbutin, which has been shown to kill bacteria in the urine 35. Urinary excretion and metabolism of arbutin after oral. Bearberry uvaursi health benefits and side effects. Massachusetts a disease resistant selection with smaller leaves than the species. The most representative constituent of this herbal drug is arbutin that is rapidly absorbed in the small intestine and undergoes hepatic conjugation to form hydroquinone hq conjugates. Bearberry comes from its genus arctostaphylos, from the greek word for bear arktos and staphylos a bunch of grapes, which its berries resemble. Arctostaphylos uvaursi is a plant species of the genus arctostaphylos manzanita. Habitatthe bearberry arctostaphylos uva ursi, sprengel, a small shrub, with decumbent, much branched, irregular stems and evergreen leaves, is distributed over the greater part of the northern hemisphere, being found in the northern latitudes and high mountains of europe, asia and america. Shiny leathery dark green leaves may become reddishbrown during the winter. Molecular phylogeny and phytochemistry of the genus. A partially dehydrated decoction made from bearberry may be applied as a salve to canker sores, sore gums, burns, and minor cuts. Uva ursi contains hydroquinone glycosides particularly arbutin, polyphenols, flavonoids and other compounds which. Pdf risk assessment of free hydroquinone derived from. Request pdf urinary excretion and metabolism of arbutin after oral administration of.
It is one of several related species referred to as bearberry its specific name uva ursi means grape of the bear in latin uva ursi. The leaf extract of arctostaphylos uva ursi uva ursi or bearberry has been approved for use for urinary tract inflammation by the german federal institute for drugs and medical devices and is available on prescription in germany for this indication. Bearberries look like lingonberries vaccinium vitis. Both the crude leaf extract and arbutin have demonstrated in vitro. Vancouver jade kinnikinnick arctostaphylos uva ursi vancouver jade plant details.